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Impact of the NO-Sensitive Guanylyl Cyclase 1 and 2 on Renal Blood Flow and Systemic Blood Pressure in Mice

Nitric oxide (NO) modulates renal blood flow (RBF) and kidney function and is involved in blood pressure (BP) regulation predominantly via stimulation of the NO-sensitive guanylyl cyclase (NO-GC), existing in two isoforms, NO-GC1 and NO-GC2. Here, we used isoform-specific knockout (KO) mice and inve...

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Detalles Bibliográficos
Autores principales: Mergia, Evanthia, Thieme, Manuel, Hoch, Henning, Daniil, Georgios, Hering, Lydia, Yakoub, Mina, Scherbaum, Christina Rebecca, Rump, Lars Christian, Koesling, Doris, Stegbauer, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979494/
https://www.ncbi.nlm.nih.gov/pubmed/29570672
http://dx.doi.org/10.3390/ijms19040967