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Impact of the NO-Sensitive Guanylyl Cyclase 1 and 2 on Renal Blood Flow and Systemic Blood Pressure in Mice
Nitric oxide (NO) modulates renal blood flow (RBF) and kidney function and is involved in blood pressure (BP) regulation predominantly via stimulation of the NO-sensitive guanylyl cyclase (NO-GC), existing in two isoforms, NO-GC1 and NO-GC2. Here, we used isoform-specific knockout (KO) mice and inve...
Autores principales: | Mergia, Evanthia, Thieme, Manuel, Hoch, Henning, Daniil, Georgios, Hering, Lydia, Yakoub, Mina, Scherbaum, Christina Rebecca, Rump, Lars Christian, Koesling, Doris, Stegbauer, Johannes |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979494/ https://www.ncbi.nlm.nih.gov/pubmed/29570672 http://dx.doi.org/10.3390/ijms19040967 |
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