St. John’s Wort Regulates Proliferation and Apoptosis in MCF-7 Human Breast Cancer Cells by Inhibiting AMPK/mTOR and Activating the Mitochondrial Pathway

St. John’s Wort (SJW) has been used as an estrogen agonist in the systems affected by menopause. Also, hypericin, a bioactive compound of SJW, has been used as a photosensitizer in photodynamic therapy. In the present study, we investigate the anti-proliferative and pro-apoptotic effects of SJW to d...

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Detalles Bibliográficos
Autores principales: You, Mi-Kyoung, Kim, Hwa-Jin, Kook, Ji Hyun, Kim, Hyeon-A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979501/
https://www.ncbi.nlm.nih.gov/pubmed/29570671
http://dx.doi.org/10.3390/ijms19040966

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979501/
https://www.ncbi.nlm.nih.gov/pubmed/29570671
http://dx.doi.org/10.3390/ijms19040966

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