Protective Effects of Gomisin N against Hepatic Cannabinoid Type 1 Receptor-Induced Insulin Resistance and Gluconeogenesis

Activation of the hepatic cannabinoid type 1 receptor (CB1R) induces insulin resistance and gluconeogenesis via endoplasmic reticulum (ER) stress, thereby contributing to hyperglycemia. Gomisin N (GN) is a phytochemical derived from Schisandra chinensis. In the current study, we investigated the inh...

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Detalles Bibliográficos
Autores principales: Nagappan, Arulkumar, Jung, Dae Young, Kim, Ji-Hyun, Jung, Myeong Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979504/
https://www.ncbi.nlm.nih.gov/pubmed/29570673
http://dx.doi.org/10.3390/ijms19040968

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979504/
https://www.ncbi.nlm.nih.gov/pubmed/29570673
http://dx.doi.org/10.3390/ijms19040968

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