TASK-3 Downregulation Triggers Cellular Senescence and Growth Inhibition in Breast Cancer Cell Lines

TASK-3 potassium channels are believed to promote proliferation and survival of cancer cells, in part, by augmenting their resistance to both hypoxia and serum deprivation. While overexpression of TASK-3 is frequently observed in cancers, the understanding of its role and regulation during tumorigen...

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Detalles Bibliográficos
Autores principales: Zúñiga, Rafael, Valenzuela, Claudio, Concha, Guierdy, Brown, Nelson, Zúñiga, Leandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979529/
https://www.ncbi.nlm.nih.gov/pubmed/29596383
http://dx.doi.org/10.3390/ijms19041033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979529/
https://www.ncbi.nlm.nih.gov/pubmed/29596383
http://dx.doi.org/10.3390/ijms19041033

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