Cargando…
TASK-3 Downregulation Triggers Cellular Senescence and Growth Inhibition in Breast Cancer Cell Lines
TASK-3 potassium channels are believed to promote proliferation and survival of cancer cells, in part, by augmenting their resistance to both hypoxia and serum deprivation. While overexpression of TASK-3 is frequently observed in cancers, the understanding of its role and regulation during tumorigen...
Autores principales: | Zúñiga, Rafael, Valenzuela, Claudio, Concha, Guierdy, Brown, Nelson, Zúñiga, Leandro |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979529/ https://www.ncbi.nlm.nih.gov/pubmed/29596383 http://dx.doi.org/10.3390/ijms19041033 |
Ejemplares similares
-
The Insensitivity of TASK-3 K(2)P Channels to External Tetraethylammonium (TEA) Partially Depends on the Cap Structure
por: Concha, Guierdy, et al.
Publicado: (2018) -
Correction: Concha, G., et al. The Insensitivity of TASK-3 K(2)P Channels to External Tetraethylammonium (TEA) Partially Depends on the Cap Structure. Int. J. Mol. Sci. 2018, 19, 2437
por: Concha, Guierdy, et al.
Publicado: (2019) -
HCN Channels: New Therapeutic Targets for Pain Treatment
por: Ramírez, David, et al.
Publicado: (2018) -
Elucidating the Structural Basis of the Intracellular pH Sensing Mechanism of TASK-2 K(2)P Channels
por: Bustos, Daniel, et al.
Publicado: (2020) -
Discovery of Novel TASK-3 Channel Blockers Using a Pharmacophore-Based Virtual Screening
por: Ramírez, David, et al.
Publicado: (2019)