Oxymatrine Inhibits Influenza A Virus Replication and Inflammation via TLR4, p38 MAPK and NF-κB Pathways

Oxymatrine (OMT) is a strong immunosuppressive agent that has been used in the clinic for many years. In the present study, by using plaque inhibition, luciferase reporter plasmids, qRT-PCR, western blotting, and ELISA assays, we have investigated the effect and mechanism of OMT on influenza A virus...

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Detalles Bibliográficos
Autores principales: Dai, Jian-Ping, Wang, Qian-Wen, Su, Yun, Gu, Li-Ming, Deng, Hui-Xiong, Chen, Xiao-Xuan, Li, Wei-Zhong, Li, Kang-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979549/
https://www.ncbi.nlm.nih.gov/pubmed/29570670
http://dx.doi.org/10.3390/ijms19040965

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979549/
https://www.ncbi.nlm.nih.gov/pubmed/29570670
http://dx.doi.org/10.3390/ijms19040965

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