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Oxymatrine Inhibits Influenza A Virus Replication and Inflammation via TLR4, p38 MAPK and NF-κB Pathways
Oxymatrine (OMT) is a strong immunosuppressive agent that has been used in the clinic for many years. In the present study, by using plaque inhibition, luciferase reporter plasmids, qRT-PCR, western blotting, and ELISA assays, we have investigated the effect and mechanism of OMT on influenza A virus...
Autores principales: | Dai, Jian-Ping, Wang, Qian-Wen, Su, Yun, Gu, Li-Ming, Deng, Hui-Xiong, Chen, Xiao-Xuan, Li, Wei-Zhong, Li, Kang-Sheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979549/ https://www.ncbi.nlm.nih.gov/pubmed/29570670 http://dx.doi.org/10.3390/ijms19040965 |
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