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Assembly and Functional Analysis of an S/MAR Based Episome with the Cystic Fibrosis Transmembrane Conductance Regulator Gene

Improving the efficacy of gene therapy vectors is still an important goal toward the development of safe and efficient gene therapy treatments. S/MAR (scaffold/matrix attached region)-based vectors are maintained extra-chromosomally in numerous cell types, which is similar to viral-based vectors. Ad...

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Detalles Bibliográficos
Autores principales: De Rocco, Davide, Pompili, Barbara, Castellani, Stefano, Morini, Elena, Cavinato, Luca, Cimino, Giuseppe, Mariggiò, Maria A, Guarnieri, Simone, Conese, Massimo, Del Porto, Paola, Ascenzioni, Fiorentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979583/
https://www.ncbi.nlm.nih.gov/pubmed/29673202
http://dx.doi.org/10.3390/ijms19041220