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Loss of ISWI Function in Drosophila Nuclear Bodies Drives Cytoplasmic Redistribution of Drosophila TDP-43

Over the past decade, evidence has identified a link between protein aggregation, RNA biology, and a subset of degenerative diseases. An important feature of these disorders is the cytoplasmic or nuclear aggregation of RNA-binding proteins (RBPs). Redistribution of RBPs, such as the human TAR DNA-bi...

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Detalles Bibliográficos
Autores principales: Lo Piccolo, Luca, Bonaccorso, Rosa, Attardi, Andrea, Li Greci, Lorenzo, Romano, Giulia, Sollazzo, Martina, Giurato, Giorgio, Ingrassia, Antonia Maria Rita, Feiguin, Fabian, Corona, Davide F. V., Onorati, Maria Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979594/
https://www.ncbi.nlm.nih.gov/pubmed/29617352
http://dx.doi.org/10.3390/ijms19041082