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Crystal Structure of the Isocitrate Dehydrogenase 2 from Acinetobacter baumannii (AbIDH2) Reveals a Novel Dimeric Structure with Two Monomeric-IDH-Like Subunits

Monomeric isocitrate dehydrogenases (IDHs) have a single polypeptide sizing around 85 kDa. The IDH2 from the opportunistic bacterium Acinetobacter baumannii (AbIDH2) with a mass of 83 kDa was formerly recognized as a typical monomeric IDH. However, both size exclusion chromatography and analytical u...

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Detalles Bibliográficos
Autores principales: Wang, Peng, Wu, Yatao, Liu, Jie, Song, Ping, Li, Shan, Zhou, Xinxin, Zhu, Guoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979607/
https://www.ncbi.nlm.nih.gov/pubmed/29642588
http://dx.doi.org/10.3390/ijms19041131