Mechanisms of Diabetes-Induced Endothelial Cell Senescence: Role of Arginase 1

We have recently found that diabetes-induced premature senescence of retinal endothelial cells is accompanied by NOX2-NADPH oxidase-induced increases in the ureohydrolase enzyme arginase 1 (A1). Here, we used genetic strategies to determine the specific involvement of A1 in diabetes-induced endothel...

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Detalles Bibliográficos
Autores principales: Shosha, Esraa, Xu, Zhimin, Narayanan, S. Priya, Lemtalsi, Tahira, Fouda, Abdelrahman Y., Rojas, Modesto, Xing, Ji, Fulton, David, Caldwell, R. William, Caldwell, Ruth B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979610/
https://www.ncbi.nlm.nih.gov/pubmed/29673160
http://dx.doi.org/10.3390/ijms19041215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979610/
https://www.ncbi.nlm.nih.gov/pubmed/29673160
http://dx.doi.org/10.3390/ijms19041215

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