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Cannabidiol exerts antiepileptic effects by restoring hippocampal interneuron functions in a temporal lobe epilepsy model

BACKGROUND AND PURPOSE: A non‐psychoactive phytocannabinoid, cannabidiol (CBD), shows promising results as an effective potential antiepileptic drug in some forms of refractory epilepsy. To elucidate the mechanisms by which CBD exerts its anti‐seizure effects, we investigated its effects at synaptic...

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Detalles Bibliográficos
Autores principales: Khan, Archie A, Shekh‐Ahmad, Tawfeeq, Khalil, Ayatakin, Walker, Matthew C, Ali, Afia B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979781/
https://www.ncbi.nlm.nih.gov/pubmed/29574880
http://dx.doi.org/10.1111/bph.14202