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Slow‐Release Formulation of Cowpea Mosaic Virus for In Situ Vaccine Delivery to Treat Ovarian Cancer

The plant viral nanoparticle cowpea mosaic virus (CPMV) is shown to be an effective immunotherapy for ovarian cancer when administered as in situ vaccine weekly, directly into the intraperitoneal (IP) space in mice with disseminated tumors. While the antitumor efficacy is promising, the required fre...

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Detalles Bibliográficos
Autores principales: Czapar, Anna E., Tiu, Brylee David B., Veliz, Frank A., Pokorski, Jonathan K., Steinmetz, Nicole F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979803/
https://www.ncbi.nlm.nih.gov/pubmed/29876220
http://dx.doi.org/10.1002/advs.201700991