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miR-19a/b and MeCP2 repress reciprocally to regulate multidrug resistance in gastric cancer cells

Despite the improvement in gastric cancer (GC) treatment, multidrug resistance (MDR) is still a significant reason for chemotherapy failure. Our previous studies have demonstrated that miR-19a/b upregulation directly promoted MDR in GC cells. However, the exact regulation and the potential molecule...

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Detalles Bibliográficos
Autores principales: Zhu, Fei, Wu, Qiong, Ni, Zhen, Lei, Chao, Li, Ting, Shi, Yongquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979884/
https://www.ncbi.nlm.nih.gov/pubmed/29568890
http://dx.doi.org/10.3892/ijmm.2018.3581