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Lack of endogenous parathyroid hormone delays fracture healing by inhibiting vascular endothelial growth factor-mediated angiogenesis

Intermittent low-dose injections of parathyroid hormone (PTH) have been reported to exert bone anabolic effects and to promote fracture healing. As an important proangiogenic cytokine, vascular endothelial growth factor (VEGF) is secreted by bone marrow mesenchymal stem cells (BMSCs) and osteoblasts...

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Detalles Bibliográficos
Autores principales: Ding, Qingfeng, Sun, Peng, Zhou, Hao, Wan, Bowen, Yin, Jian, Huang, Yao, Li, Qingqing, Yin, Guoyong, Fan, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979887/
https://www.ncbi.nlm.nih.gov/pubmed/29620150
http://dx.doi.org/10.3892/ijmm.2018.3614