Adenovirus-mediated knockdown of activin A receptor type 2A attenuates immune-induced hepatic fibrosis in mice and inhibits interleukin-17-induced activation of primary hepatic stellate cells

Fibrosis induces a progressive loss of liver function, thus leading to organ failure. Activins are secreted proteins that belong to the transforming growth factor (TGF)-β superfamily, which initiate signaling by binding to their two type II receptors: Activin A receptor type 2A (ACVR2A) and activin...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Hongjun, Ju, Baoling, Nie, Ying, Song, Baohui, Xu, Yuanhong, Gao, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979935/
https://www.ncbi.nlm.nih.gov/pubmed/29620144
http://dx.doi.org/10.3892/ijmm.2018.3600

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979935/
https://www.ncbi.nlm.nih.gov/pubmed/29620144
http://dx.doi.org/10.3892/ijmm.2018.3600

Ejemplares similares