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TIM-4 blockade of KCs combined with exogenous TGF-β injection helps to reverse acute rejection and prolong the survival rate of mice receiving liver allografts

An acute reaction response (AR) following liver transplantation (LT) is caused by immune responses that are primarily mediated by T lymphocytes. Kupffer cells (KCs) are the largest antigen presenting cell (APC) group in vivo and are the primary modulators of the inflammatory or tolerogenic immune re...

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Detalles Bibliográficos
Autores principales: Wu, Hao, Xu, Xuesong, Li, Jinzheng, Gong, Jianping, Li, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979939/
https://www.ncbi.nlm.nih.gov/pubmed/29620252
http://dx.doi.org/10.3892/ijmm.2018.3606