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TIM-4 blockade of KCs combined with exogenous TGF-β injection helps to reverse acute rejection and prolong the survival rate of mice receiving liver allografts
An acute reaction response (AR) following liver transplantation (LT) is caused by immune responses that are primarily mediated by T lymphocytes. Kupffer cells (KCs) are the largest antigen presenting cell (APC) group in vivo and are the primary modulators of the inflammatory or tolerogenic immune re...
Autores principales: | Wu, Hao, Xu, Xuesong, Li, Jinzheng, Gong, Jianping, Li, Min |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979939/ https://www.ncbi.nlm.nih.gov/pubmed/29620252 http://dx.doi.org/10.3892/ijmm.2018.3606 |
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