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A prominent air pollutant, Indeno[1,2,3-cd]pyrene, enhances allergic lung inflammation via aryl hydrocarbon receptor

Chronic exposure to ambient polycyclic aromatic hydrocarbons (PAHs) is associated with asthma, but its regulatory mechanisms remain incompletely defined. We report herein that elevated levels of urinary 1-hydroxypyrene, a biomarker of PAH exposure, were found in asthmatic subjects (n = 39) as compar...

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Detalles Bibliográficos
Autores principales: Wong, Tzu-Hsuan, Lee, Chon-Lin, Su, Hsiang-Han, Lee, Chin-Lai, Wu, Chao-Chien, Wang, Chin-Chou, Sheu, Chau-Chyun, Lai, Ruay-Sheng, Leung, Sum-Yee, Lin, Chi-Cheng, Wei, Yu-Feng, Wang, Chien-Jen, Lin, Yu-Chun, Chen, Hua-Ling, Huang, Ming-Shyan, Yen, Jeng-Hsien, Huang, Shau-Ku, Suen, Jau-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979946/
https://www.ncbi.nlm.nih.gov/pubmed/29581487
http://dx.doi.org/10.1038/s41598-018-23542-9