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Three-dimensional Epigenome Statistical Model: Genome-wide Chromatin Looping Prediction

This study aims to understand through statistical learning the basic biophysical mechanisms behind three-dimensional folding of epigenomes. The 3DEpiLoop algorithm predicts three-dimensional chromatin looping interactions within topologically associating domains (TADs) from one-dimensional epigenomi...

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Detalles Bibliográficos
Autores principales: Al Bkhetan, Ziad, Plewczynski, Dariusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979957/
https://www.ncbi.nlm.nih.gov/pubmed/29581440
http://dx.doi.org/10.1038/s41598-018-23276-8