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Engineered 3D vascular and neuronal networks in a microfluidic platform

Neurovascular coupling plays a key role in the pathogenesis of neurodegenerative disorders including motor neuron disease (MND). In vitro models provide an opportunity to understand the pathogenesis of MND, and offer the potential for drug screening. Here, we describe a new 3D microvascular and neur...

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Detalles Bibliográficos
Autores principales: Osaki, Tatsuya, Sivathanu, Vivek, Kamm, Roger D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979969/
https://www.ncbi.nlm.nih.gov/pubmed/29581463
http://dx.doi.org/10.1038/s41598-018-23512-1