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Furin inhibitor protects against neuronal cell death induced by activated NMDA receptors

The proprotein convertases (PCs) act as serine proteases and are known to convert diverse precursor proteins into their active forms. Among the PCs, furin has been considered to play a crucial role not only in embryogenesis, but also in the initiation and progression of certain pathologic conditions...

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Detalles Bibliográficos
Autores principales: Yamada, Mariko, Hayashi, Hideki, Yuuki, Moe, Matsushima, Nahoko, Yuan, Bo, Takagi, Norio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980093/
https://www.ncbi.nlm.nih.gov/pubmed/29581474
http://dx.doi.org/10.1038/s41598-018-23567-0