Cargando…
Furin inhibitor protects against neuronal cell death induced by activated NMDA receptors
The proprotein convertases (PCs) act as serine proteases and are known to convert diverse precursor proteins into their active forms. Among the PCs, furin has been considered to play a crucial role not only in embryogenesis, but also in the initiation and progression of certain pathologic conditions...
Autores principales: | Yamada, Mariko, Hayashi, Hideki, Yuuki, Moe, Matsushima, Nahoko, Yuan, Bo, Takagi, Norio |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980093/ https://www.ncbi.nlm.nih.gov/pubmed/29581474 http://dx.doi.org/10.1038/s41598-018-23567-0 |
Ejemplares similares
-
Furin-mediated cleavage of LRP1 and increase in ICD of LRP1 after cerebral ischemia and after exposure of cultured neurons to NMDA
por: Yamada, Mariko, et al.
Publicado: (2019) -
Apolipoprotein E-Containing Lipoproteins and LRP1 Protect From NMDA-Induced Excitotoxicity Associated With Reducing α2-Macroglobulin in Müller Glia
por: Hayashi, Hideki, et al.
Publicado: (2021) -
The Neuroprotective Effect of Thalidomide against Ischemia through the Cereblon-mediated Repression of AMPK Activity
por: Sawamura, Naoya, et al.
Publicado: (2018) -
Investigating the Relationship Between Neuronal Cell Death and Early DNA Methylation After Ischemic Injury
por: Asada, Mayumi, et al.
Publicado: (2020) -
Scaffolding protein Homer1a protects against NMDA-induced neuronal injury
por: Wang, Y, et al.
Publicado: (2015)