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Innate immune system activation in zebrafish and cellular models of Diamond Blackfan Anemia

Deficiency of ribosomal proteins (RPs) leads to Diamond Blackfan Anemia (DBA) associated with anemia, congenital defects, and cancer. While p53 activation is responsible for many features of DBA, the role of immune system is less defined. The Innate immune system can be activated by endogenous nucle...

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Detalles Bibliográficos
Autores principales: Danilova, Nadia, Wilkes, Mark, Bibikova, Elena, Youn, Min-Young, Sakamoto, Kathleen M., Lin, Shuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980095/
https://www.ncbi.nlm.nih.gov/pubmed/29581525
http://dx.doi.org/10.1038/s41598-018-23561-6