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Innate immune system activation in zebrafish and cellular models of Diamond Blackfan Anemia
Deficiency of ribosomal proteins (RPs) leads to Diamond Blackfan Anemia (DBA) associated with anemia, congenital defects, and cancer. While p53 activation is responsible for many features of DBA, the role of immune system is less defined. The Innate immune system can be activated by endogenous nucle...
Autores principales: | Danilova, Nadia, Wilkes, Mark, Bibikova, Elena, Youn, Min-Young, Sakamoto, Kathleen M., Lin, Shuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980095/ https://www.ncbi.nlm.nih.gov/pubmed/29581525 http://dx.doi.org/10.1038/s41598-018-23561-6 |
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