Loss of Stemness, EMT, and Supernumerary Tooth Formation in Cebpb(−/−)Runx2(+/−) Murine Incisors

Adult Cebpb KO mice incisors present amelogenin-positive epithelium pearls, enamel and dentin allopathic hyperplasia, fewer Sox2-positive cells in labial cervical loop epitheliums, and reduced Sox2 expression in enamel epithelial stem cells. Thus, Cebpb acts upstream of Sox2 to regulate stemness. In...

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Detalles Bibliográficos
Autores principales: Saito, Kazuyuki, Takahashi, Katsu, Huang, Boyen, Asahara, Masakazu, Kiso, Honoka, Togo, Yumiko, Tsukamoto, Hiroko, Mishima, Sayaka, Nagata, Masaki, Iida, Machiko, Tokita, Yoshihito, Asai, Masato, Shimizu, Akira, Komori, Toshihisa, Harada, Hidemitsu, MacDougall, Mary, Sugai, Manabu, Bessho, Kazuhisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980103/
https://www.ncbi.nlm.nih.gov/pubmed/29581460
http://dx.doi.org/10.1038/s41598-018-23515-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980103/
https://www.ncbi.nlm.nih.gov/pubmed/29581460
http://dx.doi.org/10.1038/s41598-018-23515-y

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