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Effect of a mitochondrial‐targeted coenzyme Q analog on pancreatic β‐cell function and energetics in high fat fed obese mice

We recently reported that mitoquinone (mitoQ, 500 μmol/L) added to drinking water of C57BL/6J mice attenuated weight gain and reduced oxidative stress when administered to high‐fat (HF) fed mice. Here, we examined the effects of mitoQ administered to HF fed mice on pancreatic islet morphology, dynam...

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Detalles Bibliográficos
Autores principales: Imai, Yumi, Fink, Brian D., Promes, Joseph A., Kulkarni, Chaitanya A., Kerns, Robert J., Sivitz, William I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980123/
https://www.ncbi.nlm.nih.gov/pubmed/29864244
http://dx.doi.org/10.1002/prp2.393