Humanization of fibroblast growth factor 1 single‐chain antibody and validation for its antitumorigenic efficacy in breast cancer and glioma cells

Single‐chain variable fragment (scFv) antibodies are the smallest immunoglobulins with high antigen‐binding affinity. We have previously reported that fibroblast growth factor 1 played pivotal roles in cancer development and generated a mouse scFv (mscFv1C9) could effectively prohibit cancer cell pr...

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Detalles Bibliográficos
Autores principales: He, Xiao‐Xiao, Du, Shuang, Gao, Shi‐Qian, Chen, Jing‐Ying, Cao, Ran‐Juan, Xing, Zhen‐Kai, Kazim, Alia Rizvi Syeda, Yu, Hua‐Li, Zheng, Qing‐Chuan, Zhu, Xiao‐Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980129/
https://www.ncbi.nlm.nih.gov/pubmed/29575613
http://dx.doi.org/10.1111/jcmm.13547

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980129/
https://www.ncbi.nlm.nih.gov/pubmed/29575613
http://dx.doi.org/10.1111/jcmm.13547

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