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Humanization of fibroblast growth factor 1 single‐chain antibody and validation for its antitumorigenic efficacy in breast cancer and glioma cells
Single‐chain variable fragment (scFv) antibodies are the smallest immunoglobulins with high antigen‐binding affinity. We have previously reported that fibroblast growth factor 1 played pivotal roles in cancer development and generated a mouse scFv (mscFv1C9) could effectively prohibit cancer cell pr...
Autores principales: | He, Xiao‐Xiao, Du, Shuang, Gao, Shi‐Qian, Chen, Jing‐Ying, Cao, Ran‐Juan, Xing, Zhen‐Kai, Kazim, Alia Rizvi Syeda, Yu, Hua‐Li, Zheng, Qing‐Chuan, Zhu, Xiao‐Juan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980129/ https://www.ncbi.nlm.nih.gov/pubmed/29575613 http://dx.doi.org/10.1111/jcmm.13547 |
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