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Inhibition of yes‐associated protein suppresses brain metastasis of human lung adenocarcinoma in a murine model

Yes‐associated protein (YAP) is a main mediator of the Hippo pathway and promotes cancer development and progression in human lung cancer. We sought to determine whether inhibition of YAP suppresses metastasis of human lung adenocarcinoma in a murine model. We found that metastatic NSCLC cell lines...

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Detalles Bibliográficos
Autores principales: Hsu, Ping‐Chih, Miao, Jinbai, Huang, Zhen, Yang, Yi‐Lin, Xu, Zhidong, You, Joanna, Dai, Yuyuan, Yeh, Che‐Chung, Chan, Geraldine, Liu, Shu, Urisman, Anatoly, Yang, Cheng‐Ta, Jablons, David M., You, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980132/
https://www.ncbi.nlm.nih.gov/pubmed/29575527
http://dx.doi.org/10.1111/jcmm.13582