S1PR3 is essential for phosphorylated fingolimod to protect astrocytes against oxygen‐glucose deprivation‐induced neuroinflammation via inhibiting TLR2/4‐NFκB signalling

Fingolimod (FTY720) is used as an immunosuppressant for multiple sclerosis. Numerous studies indicated its neuroprotective effects in stroke. However, the mechanism remains to be elucidated. This study was intended to investigate the mechanisms of phosphorylated FTY720 (pFTY720), which was the princ...

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Detalles Bibliográficos
Autores principales: Dong, Yin‐Feng, Guo, Ruo‐Bing, Ji, Juan, Cao, Lu‐Lu, Zhang, Ling, Chen, Zheng‐Zhen, Huang, Ji‐Ye, Wu, Jin, Lu, Jun, Sun, Xiu‐Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980137/
https://www.ncbi.nlm.nih.gov/pubmed/29536648
http://dx.doi.org/10.1111/jcmm.13596

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980137/
https://www.ncbi.nlm.nih.gov/pubmed/29536648
http://dx.doi.org/10.1111/jcmm.13596

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