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Activation of AMPK by simvastatin inhibited breast tumor angiogenesis via impeding HIF‐1α‐induced pro‐angiogenic factor

Substantial data from preclinical studies have revealed the biphasic effects of statins on cardiovascular angiogenesis. Although some have reported the anti‐angiogenic potential of statins in malignant tumors, the underlying mechanism remains poorly understood. The aim of this study is to elucidate...

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Detalles Bibliográficos
Autores principales: Wang, Ji‐Chang, Li, Xiong‐Xiong, Sun, Xin, Li, Guang‐Yue, Sun, Jing‐Lan, Ye, Yuan‐Peng, Cong, Long‐Long, Li, Wei‐Ming, Lu, Shao‐Ying, Feng, Jun, Liu, Pei‐Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980150/
https://www.ncbi.nlm.nih.gov/pubmed/29532562
http://dx.doi.org/10.1111/cas.13570