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Pim1 supports human colorectal cancer growth during glucose deprivation by enhancing the Warburg effect

Cancer cells metabolize glucose mainly by glycolysis and are well adapted to metabolic stress. Pim1 is an oncogene that promotes colorectal cancer (CRC) growth and metastasis, and its expression is positively correlated with CRC progression. However, the mechanism underlying Pim1 overexpression duri...

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Detalles Bibliográficos
Autores principales: Zhang, Meng, Liu, Tingting, Sun, Hui, Weng, Weiwei, Zhang, Qiongyan, Liu, Chenchen, Han, Yang, Sheng, Weiqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980151/
https://www.ncbi.nlm.nih.gov/pubmed/29516572
http://dx.doi.org/10.1111/cas.13562