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Vav1 is necessary for PU.1 mediated upmodulation of miR‐29b in acute myeloid leukaemia‐derived cells

It has been recently demonstrated that high pre‐treatment levels of miR‐29b positively correlated with the response of patients with acute myeloid leukaemia (AML) to hypomethylating agents. Upmodulation of miR‐29b by restoring its transcriptional machinery appears indeed a tool to improve therapeuti...

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Detalles Bibliográficos
Autores principales: Vezzali, Federica, Grassilli, Silvia, Lambertini, Elisabetta, Brugnoli, Federica, Patergnani, Simone, Nika, Ervin, Piva, Roberta, Pinton, Paolo, Capitani, Silvano, Bertagnolo, Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980196/
https://www.ncbi.nlm.nih.gov/pubmed/29532991
http://dx.doi.org/10.1111/jcmm.13594