Cargando…
Vav1 is necessary for PU.1 mediated upmodulation of miR‐29b in acute myeloid leukaemia‐derived cells
It has been recently demonstrated that high pre‐treatment levels of miR‐29b positively correlated with the response of patients with acute myeloid leukaemia (AML) to hypomethylating agents. Upmodulation of miR‐29b by restoring its transcriptional machinery appears indeed a tool to improve therapeuti...
Autores principales: | Vezzali, Federica, Grassilli, Silvia, Lambertini, Elisabetta, Brugnoli, Federica, Patergnani, Simone, Nika, Ervin, Piva, Roberta, Pinton, Paolo, Capitani, Silvano, Bertagnolo, Valeria |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980196/ https://www.ncbi.nlm.nih.gov/pubmed/29532991 http://dx.doi.org/10.1111/jcmm.13594 |
Ejemplares similares
-
Protective role of all-trans retinoic acid (ATRA) against hypoxia-induced malignant potential of non-invasive breast tumor derived cells
por: Al-Qassab, Yasamin, et al.
Publicado: (2018) -
Vav1 Sustains the In Vitro Differentiation of Normal and Tumor Precursors to Insulin Producing Cells Induced by all-Trans Retinoic Acid (ATRA)
por: Brugnoli, Federica, et al.
Publicado: (2020) -
Vav1 downmodulates Akt in different breast cancer subtypes: a new promising chance to improve breast cancer outcome
por: Grassilli, Silvia, et al.
Publicado: (2018) -
Vav1 Down-Modulates Akt2 Expression in Cells from Pancreatic Ductal Adenocarcinoma: Nuclear Vav1 as a Potential Regulator of Akt Related Malignancy in Pancreatic Cancer
por: Grassilli, Silvia, et al.
Publicado: (2020) -
Vav1 Selectively Down-Regulates Akt2 through miR-29b in Certain Breast Tumors with Triple Negative Phenotype
por: Grassilli, Silvia, et al.
Publicado: (2022)