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Ginsenoside Rg3 stereoisomers differentially inhibit vascular smooth muscle cell proliferation and migration in diabetic atherosclerosis

Ginsenoside 20(R/S)‐Rg3, as a natural peroxisome proliferator‐activated receptor gamma (PPARγ) ligand, has been reported to exhibit differential biological effects. It is of great interest to understand the stereochemical selectivity of 20(R/S)‐Rg3 and explore whether differential PPARγ activation b...

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Detalles Bibliográficos
Autores principales: Guo, Mengqi, Guo, Guanlun, Xiao, Jie, Sheng, Xi, Zhang, Xinyu, Tie, Yuanyuan, Cheng, Yuen‐Kit, Ji, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980205/
https://www.ncbi.nlm.nih.gov/pubmed/29566305
http://dx.doi.org/10.1111/jcmm.13601