Crystallographic observation of nonenzymatic RNA primer extension

The importance of genome replication has inspired detailed crystallographic studies of enzymatic DNA/RNA polymerization. In contrast, the mechanism of nonenzymatic polymerization is less well understood, despite its critical role in the origin of life. Here we report the direct observation of nonenz...

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Detalles Bibliográficos
Autores principales: Zhang, Wen, Walton, Travis, Li, Li, Szostak, Jack W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980232/
https://www.ncbi.nlm.nih.gov/pubmed/29851379
http://dx.doi.org/10.7554/eLife.36422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980232/
https://www.ncbi.nlm.nih.gov/pubmed/29851379
http://dx.doi.org/10.7554/eLife.36422

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