LKB1 obliterates Snail stability and inhibits pancreatic cancer metastasis in response to metformin treatment

Metastasis to distant organs is a particularly ominous feature of malignant cancer. LKB1 (also known as STK11) has been identified as a tumor suppressor in several types of cancers. Here, we show that LKB1 is at low levels and is negatively associated with poor clinical outcomes in pancreatic cancer...

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Detalles Bibliográficos
Autores principales: Song, Lele, Guo, Jingyu, Chang, Renxu, Peng, Xiaobo, Li, Jie, Xu, Xiaorong, Zhan, Xianbao, Zhan, Lixing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980291/
https://www.ncbi.nlm.nih.gov/pubmed/29601127
http://dx.doi.org/10.1111/cas.13591

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980291/
https://www.ncbi.nlm.nih.gov/pubmed/29601127
http://dx.doi.org/10.1111/cas.13591

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