Integrated Population Pharmacokinetic Analysis of Rivaroxaban Across Multiple Patient Populations

The population pharmacokinetics (PK) of rivaroxaban have been evaluated in several population‐specific models. We developed an integrated population PK model using pooled data from 4,918 patients in 7 clinical trials across all approved indications. Effects of gender, age, and weight on apparent cle...

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Detalles Bibliográficos
Autores principales: Willmann, Stefan, Zhang, Liping, Frede, Matthias, Kubitza, Dagmar, Mueck, Wolfgang, Schmidt, Stephan, Solms, Alexander, Yan, Xiaoyu, Garmann, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980303/
https://www.ncbi.nlm.nih.gov/pubmed/29660785
http://dx.doi.org/10.1002/psp4.12288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980303/
https://www.ncbi.nlm.nih.gov/pubmed/29660785
http://dx.doi.org/10.1002/psp4.12288

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