Anti‐human SIRPα antibody is a new tool for cancer immunotherapy

Interaction of signal regulatory protein α (SIRPα) expressed on the surface of macrophages with its ligand CD47 expressed on target cells negatively regulates phagocytosis of the latter cells by the former. We recently showed that blocking Abs to mouse SIRPα enhanced both the Ab‐dependent cellular p...

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Detalles Bibliográficos
Autores principales: Murata, Yoji, Tanaka, Daisuke, Hazama, Daisuke, Yanagita, Tadahiko, Saito, Yasuyuki, Kotani, Takenori, Oldenborg, Per‐Arne, Matozaki, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980332/
https://www.ncbi.nlm.nih.gov/pubmed/29473266
http://dx.doi.org/10.1111/cas.13548

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980332/
https://www.ncbi.nlm.nih.gov/pubmed/29473266
http://dx.doi.org/10.1111/cas.13548

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