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Development of a vaccine based on bacteria‐mimicking tumor cells coated with novel engineered toll‐like receptor 2 ligands

For a successful tumor vaccine, it is necessary to develop effective immuno‐adjuvants and identify specific tumor antigens. Tumor cells obtained from surgical or biopsy tissues are a good source of tumor antigens but, unlike bacteria, they do not induce strong immune responses. Here, we designed 2 n...

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Detalles Bibliográficos
Autores principales: Akazawa, Takashi, Ohashi, Toshimitsu, Wijewardana, Viskam, Sugiura, Kikuya, Inoue, Norimitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980365/
https://www.ncbi.nlm.nih.gov/pubmed/29575556
http://dx.doi.org/10.1111/cas.13576