PD-1/PD-L1 pathway: an adaptive immune resistance mechanism to immunogenic chemotherapy in colorectal cancer

Background: Chemotherapy is currently evaluated in order to enhance the efficacy of immune checkpoint blockade (ICB) therapy in colorectal cancer. However, the mechanisms by which these drugs could synergize with ICB remains unclear. The impact of chemotherapy on the PD-1/PD-L1 pathway and the resul...

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Detalles Bibliográficos
Autores principales: Dosset, Magalie, Vargas, Thaiz Rivera, Lagrange, Anaïs, Boidot, Romain, Végran, Frédérique, Roussey, Aurélie, Chalmin, Fanny, Dondaine, Lucile, Paul, Catherine, Lauret Marie-Joseph, Elodie, Martin, François, Ryffel, Bernhard, Borg, Christophe, Adotévi, Olivier, Ghiringhelli, François, Apetoh, Lionel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980491/
https://www.ncbi.nlm.nih.gov/pubmed/29872568
http://dx.doi.org/10.1080/2162402X.2018.1433981

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980491/
https://www.ncbi.nlm.nih.gov/pubmed/29872568
http://dx.doi.org/10.1080/2162402X.2018.1433981

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