Cargando…

PD-1/PD-L1 pathway: an adaptive immune resistance mechanism to immunogenic chemotherapy in colorectal cancer

Background: Chemotherapy is currently evaluated in order to enhance the efficacy of immune checkpoint blockade (ICB) therapy in colorectal cancer. However, the mechanisms by which these drugs could synergize with ICB remains unclear. The impact of chemotherapy on the PD-1/PD-L1 pathway and the resul...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dosset, Magalie, Vargas, Thaiz Rivera, Lagrange, Anaïs, Boidot, Romain, Végran, Frédérique, Roussey, Aurélie, Chalmin, Fanny, Dondaine, Lucile, Paul, Catherine, Lauret Marie-Joseph, Elodie, Martin, François, Ryffel, Bernhard, Borg, Christophe, Adotévi, Olivier, Ghiringhelli, François, Apetoh, Lionel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980491/ https://www.ncbi.nlm.nih.gov/pubmed/29872568 http://dx.doi.org/10.1080/2162402X.2018.1433981

Ejemplares similares

Modulation of Determinant Factors to Improve Therapeutic Combinations with Immune Checkpoint Inhibitors
por: Dosset, Magalie, et al.
Publicado: (2020)

T(H)9 cells in anti-tumor immunity
por: Rivera Vargas, Thaiz, et al.
Publicado: (2016)

Selective degradation of PU.1 during autophagy represses the differentiation and antitumour activity of T(H)9 cells
por: Rivera Vargas, Thaiz, et al.
Publicado: (2017)

Regulation of T cell antitumor immune response by tumor induced metabolic stress
por: Chalmin, Fanny, et al.
Publicado: (2018)

Socs3 induction by PPARγ restrains cancer-promoting inflammation
por: Végran, Frédérique, et al.
Publicado: (2013)

IRF8-dependent molecular complexes control the Th9 transcriptional program
por: Humblin, Etienne, et al.
Publicado: (2017)

Identification of a novel PD-L1 positive solid tumor transplantable in HLA-A*0201/DRB1*0101 transgenic mice
por: Rangan, Laurie, et al.
Publicado: (2017)

Bleomycin Exerts Ambivalent Antitumor Immune Effect by Triggering Both Immunogenic Cell Death and Proliferation of Regulatory T Cells
por: Bugaut, Hélène, et al.
Publicado: (2013)

Follicular helper-T cells restore CD8(+)-dependent antitumor immunity and anti-PD-L1/PD-1 efficacy
por: Niogret, Julie, et al.
Publicado: (2021)

Transcriptome analysis of T(H)2 CD4(+) T cells differentiated from wild-type and NLRP3KO mice
por: Bruchard, Mélanie, et al.
Publicado: (2015)

MER4 endogenous retrovirus correlated with better efficacy of anti-PD1/PD-L1 therapy in non-small cell lung cancer
por: Lecuelle, Julie, et al.
Publicado: (2022)

Efficiency of olaparib in colorectal cancer patients with an alteration of the homologous repair protein
por: Ghiringhelli, Francois, et al.
Publicado: (2016)

Understanding Inflammasomes and PD-1/PD-L1 Crosstalk to Improve Cancer Treatment Efficiency
por: Perrichet, Anaïs, et al.
Publicado: (2020)

GTN Enhances Antitumor Effects of Doxorubicin in TNBC by Targeting the Immunosuppressive Activity of PMN-MDSC
por: Mabrouk, Nesrine, et al.
Publicado: (2023)

Is preexisting antitumor CD4 T cell response indispensable for the chemotherapy induced immune regression of cancer?
por: Godet, Yann, et al.
Publicado: (2012)

Radiotherapy Scheme Effect on PD-L1 Expression for Locally Advanced Rectal Cancer
por: Boustani, Jihane, et al.
Publicado: (2020)

CD4 T cell-intrinsic STING signaling controls the differentiation and effector functions of T(H)1 and T(H)9 cells
por: Benoit-Lizon, Isis, et al.
Publicado: (2022)

Prognostic and predictive role of CD8 and PD-L1 determination in lung tumor tissue of patients under anti-PD-1 therapy
por: Fumet, Jean-David, et al.
Publicado: (2018)

Correction: Prognostic and predictive role of CD8 and PD-L1 determination in lung tumor tissue of patients under anti-PD-1 therapy
por: Fumet, Jean-David, et al.
Publicado: (2019)

Production of Adenosine by Ectonucleotidases: A Key Factor in Tumor Immunoescape
por: Ghiringhelli, François, et al.
Publicado: (2012)

Survivin-3B promotes chemoresistance and immune escape by inhibiting caspase-8 and -6 in cancer cells
por: Végran, Frédérique, et al.
Publicado: (2013)

Immune effects of 5-fluorouracil: Ambivalence matters
por: Ghiringhelli, François, et al.
Publicado: (2013)

The Emerging Role of IL-9 in the Anticancer Effects of Anti-PD-1 Therapy
por: Vinokurova, Daria, et al.
Publicado: (2023)

STAT3 activation: A key factor in tumor immunoescape
por: Rébé, Cédric, et al.
Publicado: (2013)

Tim-3/galectin-9 pathway and mMDSC control primary and secondary resistances to PD-1 blockade in lung cancer patients
por: Limagne, Emeric, et al.
Publicado: (2019)

Can Immunogenic Chemotherapies Relieve Cancer Cell Resistance to Immune Checkpoint Inhibitors?
por: Rivera Vargas, Thaiz, et al.
Publicado: (2019)

Personalized identification of tumor-associated immunogenic neoepitopes in hepatocellular carcinoma in complete remission after sorafenib treatment
por: Vrecko, Sindy, et al.
Publicado: (2018)

Optimized fractionated radiotherapy with anti-PD-L1 and anti-TIGIT: a promising new combination
por: Grapin, Mathieu, et al.
Publicado: (2019)

Alternative Splicing in Cancer and Immune Cells
por: Bernard, Antoine, et al.
Publicado: (2022)

Universal tumor-reactive helper peptides from telomerase as new tools for anticancer vaccination
por: Dosset, Magalie, et al.
Publicado: (2013)

IL-27-Induced Type 1 Regulatory T-Cells Produce Oxysterols that Constrain IL-10 Production
por: Vigne, Solenne, et al.
Publicado: (2017)

Tumor Infiltrating Lymphocytes Signature as a New Pan-Cancer Predictive Biomarker of Anti PD-1/PD-L1 Efficacy
por: Ballot, Elise, et al.
Publicado: (2020)

Use of dedicated gene panel sequencing using next generation sequencing to improve the personalized care of lung cancer
por: Kaderbhai, Coureche Guillaume, et al.
Publicado: (2016)

Does bevacizumab impact anti-EGFR therapy efficacy in metastatic colorectal cancer?
por: Derangère, Valentin, et al.
Publicado: (2016)

Angiotensin-converting enzyme (ACE) inhibitor prescription affects non-small-cell lung cancer (NSCLC) patients response to PD-1/PD-L1 immune checkpoint blockers
por: Medjebar, Soleine, et al.
Publicado: (2020)

A Short Caspase-3 Isoform Inhibits Chemotherapy-Induced Apoptosis by Blocking Apoptosome Assembly
por: Végran, Frédérique, et al.
Publicado: (2011)

Anti-PD-1/Anti-PD-L1 Drugs and Radiation Therapy: Combinations and Optimization Strategies
por: Boustani, Jihane, et al.
Publicado: (2021)

Distinct prognostic value of circulating anti-telomerase CD4(+) Th1 immunity and exhausted PD-1(+)/TIM-3(+) T cells in lung cancer
por: Laheurte, Caroline, et al.
Publicado: (2019)

Heat shock and HSP70 regulate 5-FU-mediated caspase-1 activation in myeloid-derived suppressor cells and tumor growth in mice
por: Pilot, Thomas, et al.
Publicado: (2020)

Uncommon EGFR mutations in lung carcinoma: features and treatment outcomes in a retrospective French cohort
por: Tankere, Pierre, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_hs5p9vatq33gk1i81etkan42pe