Outside‐In Systems Pharmacology Combines Innovative Computational Methods With High‐Throughput Whole Vertebrate Studies

To advance the systems approach in pharmacology, experimental models and computational methods need to be integrated from early drug discovery onward. Here, we propose outside‐in model development, a model identification technique to understand and predict the dynamics of a system without requiring...

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Detalles Bibliográficos
Autores principales: Schulthess, Pascal, van Wijk, Rob C., Krekels, Elke H. J., Yates, James W. T., Spaink, Herman P., van der Graaf, Piet H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980533/
https://www.ncbi.nlm.nih.gov/pubmed/29693322
http://dx.doi.org/10.1002/psp4.12297

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980533/
https://www.ncbi.nlm.nih.gov/pubmed/29693322
http://dx.doi.org/10.1002/psp4.12297

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