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The Interaction of CD97/ADGRE5 With β-Catenin in Adherens Junctions Is Lost During Colorectal Carcinogenesis

The adhesion G-protein-coupled receptor CD97/ADGRE5 is present in adherens junctions of human normal intestinal cells and upregulated in colorectal carcinomas. Here, we examined whether CD97 directly interacts with junctional proteins in normal and malignant colorectal tissue. We identified an assoc...

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Detalles Bibliográficos
Autores principales: Hilbig, Doris, Dietrich, Norman, Wandel, Elke, Gonsior, Susann, Sittig, Doreen, Hamann, Jörg, Aust, Gabriela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980956/
https://www.ncbi.nlm.nih.gov/pubmed/29888202
http://dx.doi.org/10.3389/fonc.2018.00182