The Mitochondrial Citrate Carrier (SLC25A1) Sustains Redox Homeostasis and Mitochondrial Metabolism Supporting Radioresistance of Cancer Cells With Tolerance to Cycling Severe Hypoxia

Pronounced resistance of lung cancer cells to radiotherapy and chemotherapy is a major barrier to successful treatment. Herein, both tumor hypoxia and the upregulation of the cellular antioxidant defense systems observed during malignant progression can contribute to radioresistance. We recently fou...

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Detalles Bibliográficos
Autores principales: Hlouschek, Julian, Hansel, Christine, Jendrossek, Verena, Matschke, Johann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980958/
https://www.ncbi.nlm.nih.gov/pubmed/29888201
http://dx.doi.org/10.3389/fonc.2018.00170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980958/
https://www.ncbi.nlm.nih.gov/pubmed/29888201
http://dx.doi.org/10.3389/fonc.2018.00170

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