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Short-Term Hemodynamic Effects of Apelin in Patients With Pulmonary Arterial Hypertension

Apelin agonism causes systemic vasodilatation and increased cardiac contractility in humans, and improves pulmonary arterial hypertension (PAH) in animal models. Here, the authors examined the short-term pulmonary hemodynamic effects of systemic apelin infusion in patients with PAH. In a double-blin...

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Detalles Bibliográficos
Autores principales: Brash, Lauren, Barnes, Gareth D., Brewis, Melanie J., Church, A. Colin, Gibbs, Simon J., Howard, Luke S.G.E., Jayasekera, Geeshath, Johnson, Martin K., McGlinchey, Neil, Onorato, Joelle, Simpson, Joanne, Stirrat, Colin, Thomson, Stephen, Watson, Geoffrey, Wilkins, Martin R., Xu, Carrie, Welsh, David J., Newby, David E., Peacock, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5981010/
https://www.ncbi.nlm.nih.gov/pubmed/29876530
http://dx.doi.org/10.1016/j.jacbts.2018.01.013