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Human Macrophages Escape Inhibition of Major Histocompatibility Complex-Dependent Antigen Presentation by Cytomegalovirus and Drive Proliferation and Activation of Memory CD4(+) and CD8(+) T Cells

Human cytomegalovirus (HCMV) persistently infects 40–90% of the human population but in the face of a normal immune system, viral spread and dissemination are efficiently controlled thus preventing clinically signs and disease. HCMV-infected hosts produce a remarkably large amount of HCMV-specific C...

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Detalles Bibliográficos
Autores principales: Frascaroli, Giada, Lecher, Carina, Varani, Stefania, Setz, Corinna, van der Merwe, Johannes, Brune, Wolfram, Mertens, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5981096/
https://www.ncbi.nlm.nih.gov/pubmed/29887865
http://dx.doi.org/10.3389/fimmu.2018.01129