Differential requirement for dimerization partner DP between E2F-dependent activation of tumor suppressor and growth-related genes

The transcription factor E2F plays crucial roles in cell proliferation and tumor suppression by activating growth-related genes and pro-apoptotic tumor suppressor genes, respectively. It is generally accepted that E2F binds to target sequences with its heterodimeric partner DP. Here we show that, wh...

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Detalles Bibliográficos
Autores principales: Komori, Hideyuki, Goto, Yasuko, Kurayoshi, Kenta, Ozono, Eiko, Iwanaga, Ritsuko, Bradford, Andrew P., Araki, Keigo, Ohtani, Kiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5981219/
https://www.ncbi.nlm.nih.gov/pubmed/29855511
http://dx.doi.org/10.1038/s41598-018-26860-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5981219/
https://www.ncbi.nlm.nih.gov/pubmed/29855511
http://dx.doi.org/10.1038/s41598-018-26860-0

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